AB-FUBICA

AB-FUBICA
Legal status
Legal status	CA: Schedule II; DE: NpSG (Industrial and scientific use only); UK: Class B;
Identifiers
	IUPAC name N-[(1S)-1-(Aminocarbonyl)-2-methylpropyl]-1-[(4-fluorophenyl)methyl]-1H-indole-3-carboxamide;
CAS Number	1801338-22-6 ;
ChemSpider	57427397;
UNII	U6SUE53VVY;
Chemical and physical data
Formula	C21H22FN3O2
Molar mass	367.424 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N[C@H](C(N)=O)C(C)C)C1=CN(CC2=CC=C(F)C=C2)C3=CC=CC=C31;
	InChI InChI=1S/C21H22FN3O2/c1-13(2)19(20(23)26)24-21(27)17-12-25(18-6-4-3-5-16(17)18)11-14-7-9-15(22)10-8-14/h3-10,12-13,19H,11H2,1-2H3,(H2,23,26)(H,24,27)/t19-/m0/s1; Key:KTVPQJSKKGZIEA-IBGZPJMESA-N;

AB-FUBICA is a drug that acts as a potent agonist for the cannabinoid receptors, with EC₅₀ values of 21 nM at CB₁ and 15 nM at CB₂.^[1]^[2]

References

^ Banister SD, Moir M, Stuart J, Kevin RC, Wood KE, Longworth M, et al. (September 2015). "Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA". ACS Chemical Neuroscience. 6 (9): 1546–59. doi:10.1021/acschemneuro.5b00112. PMID 26134475.
^ Qian Z, Hua Z, Liu C, Jia W (November 2015). "Four types of cannabimimetic indazole and indole derivatives, ADB-BINACA, AB-FUBICA, ADB-FUBICA, and AB-BICA, identified as new psychoactive substances". Forensic Toxicology. 34: 133–143. doi:10.1007/s11419-015-0297-2. PMC 4705129. PMID 26793280.