Singles
2011 Winston-Salem Open
Final
Champion	John Isner
Runner-up	Julien Benneteau
Score	4–6, 6–3, 6–4
Events
Singles Doubles
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Sergiy Stakhovsky was the defending champion, but lost to Julien Benneteau in the quarterfinals. John Isner defeated Benneteau in the final, 4–6, 6–3, 6–4.

All seeds received a bye into the second round.

	Quarterfinals							Semifinals							Final
	1/WC	Andy Roddick	6	6
	7	Juan Mónaco	1	4
								1/WC	Andy Roddick	67	4
								4	John Isner	79	6
	4	John Isner	1	6	6
	8	Marcos Baghdatis	6	3	4
															4	John Isner	4	6	6
															Q	Julien Benneteau	6	3	4
	10	Robin Haase	6	6
	3	Alexandr Dolgopolov	4	4
								10	Robin Haase	6	67	66
								Q	Julien Benneteau	3	79	78
	9	Sergiy Stakhovsky	6	69	2
	Q	Julien Benneteau	3	711	6

	First round							Second round							Third round							Quarterfinals
								1/WC	A Roddick	6	6
	LL	É Roger-Vasselin	77	2	77			LL	É Roger-Vasselin	2	4
		L Rosol	65	6	64										1/WC	A Roddick	6	6
		B Kavčič	6	77											15	S Giraldo	1	3
	WC	L Hewitt	4	63					B Kavčič	2	3
								15	S Giraldo	6	6
																						1/WC	A Roddick	6	6
																						7	J Mónaco	1	4
								12	P Andújar	63	2
	Q	K Nishikori	1	6	77			Q	K Nishikori	77	6
		G Müller	6	4	65										Q	K Nishikori	0	3
		T Kamke	6	6											7	J Mónaco	6	6
		A Falla	1	0					T Kamke	5	0
								7	J Mónaco	7	6

	First round							Second round							Third round							Quarterfinals
								4	J Isner	77	6
		D Sela	6	6					D Sela	63	2
		F Volandri	3	2											4	J Isner	77	6
		D Istomin	77	6											13	J Nieminen	64	2
		M Bachinger	61	1					D Istomin	6	4	4
								13	J Nieminen	3	6	6
																						4	J Isner	1	6	6
																						8	M Baghdatis	6	3	4
								11	D Tursunov	6	1	3
		S Darcis	3	6	6				S Darcis	3	6	6
		F Gil	6	3	4											S Darcis	5	0
		R Sweeting	6	7											8	M Baghdatis	7	6
		O Rochus	3	5					R Sweeting	5	1
								8	M Baghdatis	7	6

	First round							Second round							Third round							Quarterfinals
								LL	P-L Duclos	7	7
		V Hănescu	6	3	4			WC	R Harrison	5	5
	WC	R Harrison	1	6	6										LL	P-L Duclos	4	5
		M Kukushkin	5	1											10	R Haase	6	7
		J Blake	7	6					J Blake	4	1
								10	R Haase	6	6
																						10	R Haase	6	6
																						3	A Dolgopolov	4	4
								14	G Dimitrov	6	2	77
	WC	D Young	6	6				WC	D Young	4	6	62
		M Berrer	3	4											14	G Dimitrov	4	6	67
		C Berlocq	7	4											3	A Dolgopolov	6	1	79
		A Haider-Maurer	5	1r					C Berlocq	4	4
								3	A Dolgopolov	6	6

	First round							Second round							Third round							Quarterfinals
								5	N Davydenko	6	6
	Q	M Russell	6	63	6			Q	M Russell	2	2
		A Mannarino	4	77	2										5	N Davydenko	4	4
		A Golubev	6	4	6										9	S Stakhovsky	6	6
		M González	2	6	4				A Golubev	1	6	4
								9	S Stakhovsky	6	2	6
																						9	S Stakhovsky	6	69	2
																						Q	J Benneteau	3	711	6
								16	I Kunitsyn	3	1
	Q	R Mello	1	3				Q	J Benneteau	6	6
	Q	J Benneteau	6	6											Q	J Benneteau	2	6	77
		B Tomic	77	3	4											I Andreev	6	1	65
		I Andreev	65	6	6				I Andreev	7	6
								2	J Melzer	5	3

• Main Draw