The 2011 Charleston Southern Buccaneers football team represented Charleston Southern University as a member of the Big South Conference during the 2011 NCAA Division I FCS football season. Led by ninth-year head coach Jay Mills, the Buccaneers compiled an overall record of 0–11 with a mark of 0–6 in conference play, placing last out of seven teams in the Big South. It was the second winless season in program history as the team also went 0–11 in 1994.^[1] Charleston Southern played home games at Buccaneer Field in Charleston, South Carolina.

Date	Time	Opponent	Site	TV	Result	Attendance
September 3	7:00 pm	at UCF*	Bright House Networks Stadium Orlando, FL	BHSN	L 0–62	39,752
September 10	6:00 pm	at No. 4 Florida State*	Doak Campbell Stadium Tallahassee, FL	ESPN3	L 10–62	75,229
September 17	1:00 pm	at Jacksonville*	D. B. Milne Field Jacksonville, FL		L 30–37	4,185
September 24	1:30 pm	Norfolk State*	Buccaneer Field Charleston, SC		L 3–33	1,933
October 1	1:30 pm	Wesley*	Buccaneer Field Charleston, SC		L 20–32	3,186
October 15	1:30 pm	at VMI	Alumni Memorial Field Lexington, VA	ESPN3	L 17–21	7,233
October 22	1:30 pm	Liberty	Buccaneer Field Charleston, SC	WBGR-LP	L 16–38	3,375
October 29	1:30 pm	at Gardner–Webb	Ernest W. Spangler Stadium Boiling Springs, NC		L 7–14	5,570
November 5	1:30 pm	Stony Brook	Buccaneer Field Charleston, SC		L 31–50	2,806
November 12	1:30 pm	Coastal Carolina	Buccaneer Field Charleston, SC		L 38–45	2,933
November 19	1:00 pm	at Presbyterian	Bailey Memorial Stadium Clinton, SC		L 14–45	4,308
*Non-conference game Homecoming Rankings from AP Poll released prior to the game All times are in Eastern time

^[2][3]