The 2010 USA Cycling Professional Tour is the fourth year of this elite men's professional road bicycle racing series organized by USA Cycling.

David Zabriskie (342 points) and Team Columbia-HTC (469 points) are the defending champion of the overall individual and team titles, respectively.^[1]

The 2010 USA Cycling Professional Tour consists of the following 8 one-day races and stage races:^[2]

Dates Race Name Location UCI Rating Winner Team Series Leader April 18 Tour of the Battenkill Cambridge, NY 1.2  Caleb Fairly (USA) Holowesko Partners U23  Caleb Fairly (USA) May 16–23 AMGEN Tour of California California 2.HC  Michael Rogers (AUS) Team HTC–Columbia  Michael Rogers (AUS) June 6 TD Bank International Championship Philadelphia, PA 1.HC  Matthew Goss (AUS) Team HTC–Columbia  Michael Rogers (AUS) August 14 USA Cycling Professional Criterium Championships Glencoe, IL 1.1  David Veilleux (CAN) Kelly Benefit Strategies  Michael Rogers (AUS) September 11–12 Univest Grand Prix[3] Souderton, PA 1.2  Jonas Ahlstrand (SWE) Team Cykelcity  Michael Rogers (AUS) September 18 USA Cycling Professional Time Trial Championships Greenville, SC CN  Taylor Phinney (USA) Trek–Livestrong  Michael Rogers (AUS) September 19 USA Cycling Professional Road Championships Greenville, SC CN  Ben King (USA) Trek–Livestrong  Michael Rogers (AUS)