Singles
2010 St. Petersburg Open
Final
Champion	Mikhail Kukushkin
Runner-up	Mikhail Youzhny
Score	6–3, 7–6(7–2)
Events
Singles Doubles
← 2009 · St. Petersburg Open · 2011 →

Sergiy Stakhovsky was the defending champion, but lost in the first round to Benjamin Becker.
Mikhail Kukushkin defeated 1st seed Mikhail Youzhny 6–3, 7–6^(7–2) to win this tournament.

	Semifinals							Final
	1	Mikhail Youzhny	7	4	710
	WC	Dmitry Tursunov	5	6	68
								1	Mikhail Youzhny	3	62
									Mikhail Kukushkin	6	77
		Mikhail Kukushkin	6	6
		Illya Marchenko	3	4

	First round							Second round							Quarterfinals							Semifinals
	1	M Youzhny	6	6
		D Brands	4	1				1	M Youzhny	3	6	6
	WC	A Kuznetsov	5	62				Q	E Donskoy	6	3	2
	Q	E Donskoy	7	77											1	M Youzhny	65	6	78
	Q	R Ram	6	65	6										8	V Hănescu	77	3	66
		P Andújar	3	77	3			Q	R Ram	61	6	3
		H Zeballos	2	0				8	V Hănescu	77	3	6
	8	V Hănescu	6	6																		1	M Youzhny	7	4	710
	4	Y-h Lu	6	6																		WC	D Tursunov	5	6	68
		P Starace	2	2				4	Y-h Lu	1	4
	WC	D Tursunov	3	6	6			WC	D Tursunov	6	6
		M Przysiężny	6	3	2										WC	D Tursunov	6	6
		A Dolgopolov	77	6												A Dolgopolov	4	2
		F Fognini	65	4					A Dolgopolov	6	6
		R Schüttler	6	4	6				R Schüttler	4	2
	5	V Troicki	3	6	3

	First round							Second round							Quarterfinals							Semifinals
	7	J Chardy	77	1	0
		M Kukushkin	63	6	6				M Kukushkin	6	6
		F Volandri	6	3	2				T Gabashvili	3	4
		T Gabashvili	3	6	6											M Kukushkin	7	3	6
	WC	I Andreev	1	5											3	J Tipsarević	5	6	4
		M Russell	6	7					M Russell	2	5
		I Kunitsyn	4	2				3	J Tipsarević	6	7
	3	J Tipsarević	6	6																			M Kukushkin	6	6
	6	D Istomin	2	2r																			I Marchenko	3	4
		I Marchenko	6	2					I Marchenko	6	6
	Q	K Kravchuk	6	6				Q	K Kravchuk	4	4
	Q	F Čermák	2	3												I Marchenko	6	2	6
		M González	4	3												B Becker	4	6	2
		P-H Mathieu	6	6					P-H Mathieu	4	2
		B Becker	6	5	6				B Becker	6	6
	2	S Stakhovsky	4	7	4

• Main Draw
• Qualifying Draw