The 2004 Holy Cross Crusaders football team was an American football team that represented the College of the Holy Cross during the 2004 NCAA Division I-AA football season. Holy Cross finished second-to-last in the Patriot League.

In their first year under head coach Tom Gilmore, the Crusaders compiled a 3–8 record. David Mitchell and Steve Silva were the team captains.^[1]

The Crusaders were outscored 367 to 240. Their 1–5 conference record placed sixth in the seven-team Patriot League standings.^[2]

Holy Cross played its home games at Fitton Field on the college campus in Worcester, Massachusetts.

Date	Opponent	Site	Result	Attendance	Source
September 4	Duquesne*	Fitton Field Worcester, MA	L 7–31	6,478	[3]
September 11	San Diego*	Fitton Field Worcester, MA	L 31–37	5,471	[4]
September 18	at Harvard*	Harvard Stadium Boston, MA	L 0–35	9,513	[5]
October 2	Fordham	Fitton Field Worcester, MA (rivalry)	L 35–42	5,222	[6]
October 9	No. 17 Lehigh	Fitton Field Worcester, MA	L 14–42	6,826	[7]
October 16	at Dartmouth*	Memorial Field Hanover, NH	W 24–0	3,116	[8]
October 23	at No. 18 Colgate	Andy Kerr Stadium Hamilton, NY	L 7–41	9,228	[9]
October 30	Bucknell^	Fitton Field Worcester, MA	L 27–42	4,091	[10]
November 6	Marist*	Fitton Field Worcester, MA	W 44–13	4,872	[11]
November 13	at Lafayette	Fisher Field Easton, PA	L 20–56	4,543	[12]
November 20	at Georgetown	Harbin Field Washington, DC	W 31–28 OT	1,870	[13]
*Non-conference game Homecoming ^ Family Weekend Rankings from The Sports Network Poll released prior to the game