The 50° Targa Florio took place on 8 May 1966, on the Circuito Piccolo delle Madonie, Sicily (Italy).^[1]

The 50th anniversary edition of the Targa was marred by an inclement weather that turned the road into a quagmire. The winners of the 1965 edition, Nino Vaccarella and Lorenzo Bandini started as favorites driving the powerful, prototype-class Ferrari 330 P3.^[1] Indeed it seemed they could led Ferrari to another victory but two laps from the end, a wrong maneuver by Bandini while lapping a slower car resulted in the 330 off the road. This paved the way of the victory for the factory-backed Scuderia Filipinetti Porsche 906 of Herbert Müller and Willy Mairesse, followed by the Dino 206 S of Guichet/Baghetti, and another 906 of Sicilian duo Pucci/Arena.^[1]

Pos	Class	No	Team	Drivers	Chassis	Laps
1	S 2.0	148	Scuderia Filipinetti/Porsche System Engineering	Herbert Müller Willy Mairesse	Porsche 906	10
2	P 2.0	196	Ferrari SEFAC	Jean Guichet Giancarlo Baghetti	Dino 206 S	10
3	S 2.0	144	Porsche System Engineering	Antonio Pucci Vincenzo Arena	Porsche 906	10

^[1]