Events from the year 1506 in England.

• Monarch – Henry VII
• Lord Chancellor – William Warham
• Lord Privy Seal – Richard Foxe
• Secretary of State – Thomas Ruthall

• 16 January – Philip of Burgundy lands at Melcombe Regis after the fleet carrying him to Castile runs into a violent storm
• 9 February and 20 March – Treaties of Windsor ally England, Burgundy, and the Habsburgs against France. These are signed by Philip while held by Henry VII at Windsor Castle
• 24 April – After being extradited to England as part of Henry's agreement with Philip, Edmund de la Pole is imprisoned in the Tower of London as a rival claimant to the throne.

• 4 December – Thomas Darcy, Courtier (died 1558)
• Elizabeth Barton, nun (died 1534)
• Margaret Lee, confidante of Queen Anne Boleyn (died 1543)
• William Paget, 1st Baron Paget, statesman (died 1563)

• 6 September – Sir Richard Guildford, courtier (born 1450)
• 8 November – Edward Hastings, 2nd Baron Hastings (born 1466)