Zyuzino (Russian: Зюзино) is the name of several rural localities in Russia:

• Zyuzino, Astrakhan Oblast, a selo in Zyuzinsky Selsoviet of Ikryaninsky District of Astrakhan Oblast
• Zyuzino, Kaluga Oblast, a village in Mosalsky District of Kaluga Oblast
• Zyuzino, Kurgan Oblast, a selo in Zyuzinsky Selsoviet of Belozersky District of Kurgan Oblast
• Zyuzino, Moscow Oblast, a selo in Vyalkovskoye Rural Settlement of Ramensky District of Moscow Oblast
• Zyuzino, Republic of Tatarstan, a selo in Rybno-Slobodsky District of the Republic of Tatarstan
• Zyuzino, Udmurt Republic, a selo in Zyuzinsky Selsoviet of Sharkansky District of the Udmurt Republic