Yolo or YOLO may refer to:

• YOLO (aphorism) ("you only live once")

• Yolo, California, an unincorporated community and census-designated place
• Yolo County, California
  • Yolo County Airport
• Yolo City, the former name of Woodland, California
• Yolo, Mali, a village

• YOLO (film), 2024 Chinese comedy drama film

• "YOLO" (The Lonely Island song), 2013
• "YOLO" (Band-Maid song), 2016
• "Yolo" (Gims song), 2020
• YOLO (album), 2017 album by South Korean pop music group Dia
• "YOLO", a song by Madtown from their 2014 EP Mad Town

• YOLO (2016 TV series), 2016 Ghanaian TV series
• YOLO (2020 TV series), 2020 animated series for Adult Swim
• "YOLO" (The Simpsons), 2013 episode
• "YOLO" (Scandal), 2013 episode of the TV series Scandal

• Yolo telescope, a type of reflecting telescope with tilted mirrors
• You Only Look Once, a series of neural networks for object detection and recognition

• Yolo (prince) (1625–1689), Manchu prince of the Qing dynasty
• Yolo Akili (born 1981), activist, writer, poet, counselor, and community organizer

• Yolo Bypass, a flood bypass in the Sacramento Valley
  • Yolo Bypass Wildlife Area, located within the Yolo Bypass
• Jolo (disambiguation)
• You Only Live Once (disambiguation)