William Meredith may refer to:

• William Meredith (MP), MP for Wootton Bassett
• Billy Meredith (1874–1958), Welsh international winger, oft described as "football's first superstar"
• William Morris Meredith Jr. (1919–2007), American poet and Pulitzer Prize laureate
• William Collis Meredith (1812–1894), Canadian jurist, Chief Justice of Quebec Superior Court
• William Morton Meredith (1835–1917), American director of the Bureau of Engraving and Printing
• William Meredith (surgeon) (1848–1916), American surgeon who practiced in Briton
• William Ralph Meredith (1840–1923), Canadian politician
• William M. Meredith (1799–1873), American lawyer, politician, and U.S. Treasury Secretary
• Sir William Meredith, 3rd Baronet (1725–1790), British politician
• William Meredith (American football) (died 1959), football coach