William Ashley may refer to:

• William Ashley (economic historian) (1860–1927), English economic historian
• Bill Ashley (politician) (1881–1958), Australian politician
• William Henry Ashley (1778–1838), American fur trader, entrepreneur, and politician
• Gobo Ashley (William Hare Ashley, 1862–1930), South African cricketer
• Billy Ashley (born 1970), American baseball player

• William Ashley-Brown (1880–1970), Australian Anglican priest
• William Ashley-Cooper (1803–1877), MP for Dorchester