West Siberian can refer to:

• West Siberian Plain, the world's largest unbroken lowland
• West Siberian economic region, one of twelve economic regions of Russia
• West Siberian Glacial Lake, a periglacial lake formed approximately 80,000 years ago
• West Siberian Krai, an early krai of Russian SFSR
• West Siberian Laika, a hunting dog breed developed by the indigenous people of Northern Ural and West Siberia
• Altai gas pipeline, a proposed natural gas pipeline to export natural gas from Russia's Western Siberia to North-Western China.