Virtue is the surname of:

• Brock Virtue (born 1986), Canadian curler
• Doreen Virtue (born 1958), American New Age author
• Erin Virtue (born 1983), American volleyball coach
• George Virtue (died 1868), London publisher
• Jake Virtue (1865–1943), American Major League Baseball player
• James Sprent Virtue (1829–1892), British publisher, son of George Virtue
• John Virtue (born 1947), English artist
• Keith Virtue (1909–1980), Australian pioneer aviator
• Mickey Virtue, member of the British reggae/pop band UB40
• Tarita Virtue (born 1970), successful actress and model
• Tessa Virtue (born 1989), Canadian ice dancer, 3 Olympic gold medals and 2 Olympic silver medals
• Tom Virtue (born 1957), American actor

• Vertue