Vesicle may refer to:

In cellular biology or chemistry

• Vesicle (biology and chemistry), a supramolecular assembly of lipid molecules, like a cell membrane
• Synaptic vesicle

In human embryology

• Vesicle (embryology), bulge-like features of the early neural tube during embryonic brain development
• Auditory vesicle
• Optic vesicles

In human anatomy and morphology

• Seminal vesicle
• Vesicle (dermatology), a liquid-filled cavity under the epidermis, commonly called a blister

In non-human morphology

• Subsporangial vesicle
• Juice vesicles, the pulp found in the endocarp of common citrus members

In geology

• Vesicular texture, a small enclosed cavity found in some volcanic rock, such as basalt

• Vesical (disambiguation)