This Is It may refer to:

• This Is It (novel), a 1996 novel by Joseph Connolly
• This Is It, a 1956 novel by Hal Ellson

• Michael Jackson's This Is It (album) or the title song (see below), 2009
  • This Is It (concert residency), a 2009–2010 planned series of concerts
  • Michael Jackson's This Is It, a 2009 film documenting Jackson's rehearsals for the concerts
• This Is It (Jack Ingram album), 2007
• This Is It (Jimmy Ibbotson album), 1999
• This Is It (Melba Moore album) or the title song (see below), 1976
• This Is It: The Best of Faith No More, 2003
• This Is It: The Very Best Of, by Dannii Minogue, 2013
• This Is It! (The A&M Years 1979–1989), by Joe Jackson, 1997
• This Is It, by Bride, 2003
• This Is It!, by Betty Davis, 2005
• This Is It! (Bob Newhart album), by Joe Jackson, 1967
• This Is It, by Six, 2002

• "This Is It" (Kenny Loggins song), 1979
• "This Is It" (Jim Reeves song), 1965
• "This Is It" (Melba Moore song), 1976; covered by Dannii Minogue, 1993
• "This Is It" (Michael Jackson song), 2009
  • "This Is It", an unreleased song recorded by Michael Jackson, unrelated to the above, 1984
• "This Is It" (Ryan Adams song), 2004
• "This Is It" (Scotty McCreey song), 2018
• "This Is It" (Staind song), 2009
• "This Is It", by Billy Preston from That's the Way God Planned It, 1969
• "This Is It", by Innosense from So Together, 2000
• "This Is It", by Jay and the Americans, 1962
• "This Is It", by Lo Moon from Lo Moon, 2018

• This Is It (TV series), a 2016–2017 Nigerian drama series
• This Is It, a 1960s Australian variety program on ATV
• "This Is It", the theme song of The Bugs Bunny Show
• "This Is It", the theme song of the 1970s American sitcom One Day at a Time
• "This Is It" (One Day at a Time episode), the first episode of the 2017 One Day at a Time remake

• This Is It! (bar), the oldest continually operating gay bar in Wisconsin, US
• This Is It Collective, a group of filmmakers best known for creating the Don't Hug Me I'm Scared series

• Diz Iz It!, a 2010 Philippine variety show
• This Is It and I Am It and You Are It and So Is That and He Is It and She Is It and It Is It and That Is That, a 2008 album by Marnie Stern
• Zehu Ze! (lit. This Is it!), an Israeli television series, 1978–1998