Taniguchi (written: 谷口 lit. "valley mouth") is the 92nd most common Japanese surname.^[1] Notable people with the surname include:

• Akemi Taniguchi (谷口 明見, born 1937), Japanese Nordic combined skier
• Brian Taniguchi (born 1951), American politician
• Gorō Taniguchi (谷口 悟朗, born 1966), Japanese anime director
• Hiromi Taniguchi (谷口 浩美, born 1960), Japanese long-distance runner
• Hiroyuki Taniguchi (谷口 博之, born 1985), Japanese footballer
• Itaru Taniguchi (谷口 到, born 1984), Japanese rugby union player
• Jiro Taniguchi (谷口 ジロー, 1947–2017), Japanese manga artist
• Kei Taniguchi (谷口 圭, born 1974), Japanese footballer
• Kotaro Taniguchi (谷口 耕太郎, born 1994), Japanese sprinter
• Makoto Taniguchi (谷口 誠, born 1930), Japanese diplomat and academic
• Masaharu Taniguchi (谷口 雅春, 1893–1985), Japanese New Thought leader
• Masami Taniguchi (谷口雅美, born 1976), Japanese volleyball player
• Masatomo Taniguchi (谷口 正朋, born 1946), Japanese basketball player
• Naomi Taniguchi (谷口 尚己), Japanese motorcycle racer
• Nobuteru Taniguchi (谷口 信輝, born 1971), Japanese racing driver
• Noriko Taniguchi (谷口 令子, born 1992), Japanese rugby sevens player
• Norio Taniguchi (谷口 紀男, 1912–1999), Japanese scientist
• Senkichi Taniguchi (谷口 千吉, 1912–2007), Japanese film director and screenwriter
• Shinya Taniguchi (谷口 晋矢, 1981–2013), Japanese swimmer
• Shogo Taniguchi (谷口 彰悟, born 1991), Japanese footballer
• Shuhei Taniguchi (谷口 周平, born 1976), better known as Maybach Taniguchi, Japanese professional wrestler
• Sumiteru Taniguchi (谷口 稜曄, 1929–2017), Japanese atomic bomb survivor and anti-nuclear activist
• Tadatsugu Taniguchi (谷口 維紹, born 1948), Japanese immunologist
• Toru Taniguchi (谷口 徹, born 1968), Japanese golfer
• Yoshio Taniguchi (谷口 吉生, 1937–2024), Japanese architect
• Yoshirō Taniguchi (谷口 吉郎, 1904–1979), Japanese architect
• Yuki Taniguchi (谷口 由紀, born 1993), Japanese shogi player
• Yukinori Taniguchi (谷口 行規, born 1968), Japanese racing driver, founder of Yuke's
• Yuya Taniguchi (谷口 雄也, born 1992), Japanese baseball player

• Harumi Taniguchi (谷口 はるみ), a character in the manga series Citrus

• 8571 Taniguchi, a main-belt asteroid