St. Catherine or St. Katherine may refer to a number of saints named Catherine, or:

• St. Catharines, a city in Ontario
• St. Catharines (federal electoral district), federal
• St. Catharines (provincial electoral district), in Ontario
• Sainte-Catherine, a city in Quebec

• St Catherine, Somerset, a village and civil parish in Somerset, England
• St Catherine's, Lincoln, an area of Lincoln, Lincolnshire, England
• St Catherine's Hill, Dorset, a hill in Dorset, England
• St. Catherine's Hill, Hampshire, a chalk hill in Hampshire, England
• St Catherine's Hill, Surrey, a sandstone hill in Surrey, England
• St. Catherine's Down, a chalk down on the Isle of Wight, England
• St Catherine's Point, the southernmost point on the Isle of Wight, England
• St. Catherine's Valley, a valley in South Gloucestershire, England
• St Catherines, Argyll, a village in Argyll and Bute, Scotland
• St Catherine's Island, Pembrokeshire, Wales
• St Katharine's by the Tower, a religious precinct in London (1147–1825)
• St Katharine Docks, a former dock and now a mixed-use district in central London

• St. Catherine, Florida, an unincorporated community
• Saint Catharine, Kentucky, an unincorporated community
• St. Catharine, Missouri, an unincorporated community
• St. Catherines Island, on the coast of Georgia
• St. Katherine's Historic District, in Davenport, Iowa
• Lake St. Catherine (Louisiana), a lake in New Orleans, Louisiana

• Saint Catherine, Egypt, a city in the South Sinai Governorate, Egypt
• Saint Catherine Parish, a parish in Middlesex, Jamaica

• St Catherine's Health Centre, in Birkenhead, Merseyside, England
• St Catherine's Hospital, Doncaster, in Doncaster, South Yorkshire, England
• St. Catherine's Hospital, Rochester a 1315 leper hospital in Rochester, Kent

• Saint Catherine's Monastery, a monastery in Saint Catherine, Egypt
• St Catharine's Convent, Augsburg, Germany
• St Catharine's Convent, Edinburgh, Scotland
• St. Catherine of Sienna Convent, a convent in Springfield, Kentucky
• St. Catherine's Priory, Lincoln, a priory in Lincolnshire, England
• St. Catherine's Priory, Ribe, a Dominican priory in Denmark
• St. Catherine's Priory, Roskilde, a Dominican priory in Denmark
• St. Katherine's Abbey, Monisternagalliaghduff, an Augustinian nunnery in County Limerick, Ireland

• St Catherine's School (disambiguation), many schools, colleges and universities
• St Catharine's College, Cambridge, a college of Cambridge University
• St Catherine's College, Oxford, a college of Oxford University
• St Katherine's School, a secondary school in Somerset, England
• St. Katherine College, a four-year undergraduate college in Encinitas, California

• Saint Catherine of Alexandria (Raphael), a c. 1507–1509 painting by Raphael
• Saint Catherine Reading, a c. 1530 painting by Correggio
• Saint Catherine (Caravaggio), a c. 1598 painting by Caravaggio

• St. Catherine (album), a 2015 album by the band Ducktails
• MV St Catherine, a 1983 ferry, crossing Portsmouth to Fishbourne, Isle of Wight, England
• St. Catharine (Waldorf, Maryland) or Dr. Samuel A. Mudd House, a historic house in Maryland
• St Catherine's Castle, a small device fort in Cornwall, England
• St Catherine's Court, a Tudor manor house in north of Bath, England
• St Catherine's Fort, a Palmerston fort
• St. Catherine International Airport, in Saint Catherine, Egypt
• St. Catherine's Day or Kadripäev, a celebration in Estonia
• Feast of Saint Catherine, a religious and civil celebration annually held in Italy and other locations
• Order of Saint Catherine, an award of Imperial Russia
• Order of Saint Catherine the Great Martyr, an award of Russia established in 2012
• St. Catherine, a tune by Henri F. Hemy used in hymns such as "Faith of Our Fathers Living Still" and the baptismal hymn "O Jesus Christ Our Lord Most Dear"

• St. Catherine's Church (disambiguation)
• Sainte-Catherine (disambiguation)
• St Catherine's Chapel (disambiguation)
• St Catherine's College (disambiguation)
• St. Catherine's Priory (disambiguation)
• Santa Catalina (disambiguation)
• Santa Catarina (disambiguation)
• Santa Caterina (disambiguation)
• Święta Katarzyna (disambiguation)