A skeleton is a biological system providing support in a living organism.

Skeleton or skeletons may also refer to:

• Human skeleton, human anatomy
• Skeletonization (forensics), refers to the complete decomposition of the non-bony tissues of a corpse, leading to a bare skeleton
• n-skeleton, the subcomplex of a simplicial complex or CW complex consisting of all faces of or below a certain dimension
• Skeleton (category theory), in mathematics, every category has a skeleton in which no two distinct objects are isomorphic
• Skeleton (computer programming), a style of computer programming
• Algorithmic skeleton, a style of parallel programming based on simple high-level patterns
• Skeletal animation, a computer technique used to animate 3D characters
• Topological skeleton, a digital image processing technique used to detect objects and regions within images
• Morphological skeleton in digital image processing
• Class skeleton, an outline of a class used in software engineering
• Skeletal formula, in chemistry, the skeletal structure or skeleton of a molecule
• Straight skeleton, in geometry, is a method of representing a polygon
• Skeletonizer (disambiguation), a common name for several species of moth

• Skeletons (band), an American indie rock group

• Skeleton (Abe Vigoda album) or the title song, 2008
• Skeleton (Figurines album), 2005
• Skeletons (Danzig album), 2015
• Skeletons (Hawthorne Heights album), 2010
• Skeletons (Nothingface album), 2003
• Skeletons (Sirens and Sailors album) or the title song, 2013
• Skeletons (Wednesday 13 album) or the title song, 2008
• Skeletons, by Brothers Osborne or the title song, 2020
• Skeletons, by Seven Story Drop, 2008
• Skeletons, by Pop Evil, 2023

• "Skeleton" (song), by Donghae & Eunhyuk, 2014
• "Skeletons" (Dihaj song), representing Azerbaijan at Eurovision 2017
• "Skeletons" (Stevie Wonder song), 1987
• "Skeletons" (Yeah Yeah Yeahs song), 2010
• "Skeleton", by Bloc Party from Little Thoughts, 2004
• "The Skeleton", by Quasi from Field Studies, 1999
• "Skeletons", by James Arthur from Back from the Edge, 2016
• "Skeletons", by Travis Scott from Astroworld, 2018
• "Skeletons", by Tulisa from The Female Boss, 2012

• "Skeletons" (CSI: Miami), an episode from season 4 of the American crime drama CSI: Miami
• "Skeletons", an episode of the fourth season of NCIS
• "The Skeleton", a 1979 episode of the TV sitcom The Ropers
• Skeletons (film), a 2010 film by Nick Whitfield
• Skeletons (1997 film), a television film by David DeCoteau
• The Skeleton, a fictional character from the novel Something Wicked This Way Comes

• Skeleton (sport) (or tobogganing), a fast winter sliding sport
• Skeleton (Guitar Hero), a playable character in the Xbox 360 version of the video game Guitar Hero: World Tour
• Skeleton (Dungeons & Dragons), an undead creature from the Dungeons & Dragons fantasy roleplaying game
• Skeleton+, an Atari 2600 video game in Activision Anthology

• Skeleton (undead), in fantasy, an undead, animated skeleton
• Skeleton key, a type of key
• Skeleton watch, a type of watch where the gearing is visible
• Skeleton crew or staff, a reduced number of staff working off-hours or during a labour strike
• Skeleton Creek (disambiguation)
• Skeleton suit, a 19th-century fashion in boys' clothing
• Skeleton in the closet (idiom), an undisclosed negative fact about someone

• Bone, a rigid organ that constitutes part of the vertebrate skeleton.
• Exoskeleton, an exterior skeleton
• Endoskeleton, an interior skeleton
• Hydroskeleton, a skeleton supported by fluid pressure
• Cytoskeleton, an element present in all cells of all domains of life
• Lich, sometimes mistaken as a normal skeleton
• Skelethon, an album by Aesop Rock
• Skeletor, a fictional character in Masters of the Universe