Siege of Multan may refer to,

• Siege of Multan, 1296–1297, Alauddin Khalji's conquest of Multan.
• Siege of Multan (1528), Babur annexes Langah dynasty
• Siege of Multan (1772)
• Siege of Multan (1780), Afghans reconquer Multan.
• Siege of Multan (1810), Sikhs capture Multan and Multan governor realizes tribute.
• Siege of Multan (1818), Sikhs capture Multan from the Afghans
• Siege of Multan (1848-1849), between British East India Company and the Sikh Empire.