Shirley may refer to:

• Shirley (novel), an 1849 novel by Charlotte Brontë
• Shirley (1922 film), a British silent film
• Shirley (2020 film), an American film
• Shirley (2024 film), an American biographical film about Shirley Chisholm
• Shirley (album), a 1961 album by Shirley Bassey
• "Shirley" (song), a 1958 song by John Fred and the Playboys
• Shirley (TV series), a 1979 TV series
• Shirley (manga), a 2003 manga series

• Shirley (name), a given name and a surname
• Shirley (Dutch singer) (born 1946), Dutch singer and pianist
• Szhirley (born 1976), Danish singer

• Shirley, Derbyshire, England
• Shirley, Hampshire, a hamlet in Sopley parish, New Forest
• Shirley, Southampton, a district of Southampton, Hampshire
• Shirley, London, in Croydon
• Shirley, West Midlands, England

• Shirley, Arkansas
• Shirley, Illinois
• Shirley, Indiana
• Shirley, Maine
• Shirley, Massachusetts, a New England town
  • Shirley (CDP), Massachusetts, the main village in the town
• Shirley, Minnesota
• Shirley, Missouri
• Shirley, New York, a hamlet in Suffolk County
• Shirley, Erie County, New York, a hamlet
• Shirley Plantation, an estate in Virginia
• Shirley, West Virginia
• Shirley, Wisconsin

• Shirley, New Zealand, a suburb of Christchurch
• Shirley Island, Antarctica
• Shirleys Bay, in the Ottawa River, Ontario, Canada

• Shirley railway station (England), in Shirley, West Midlands, England
• Shirley station (MBTA), in Shirley, Massachusetts, US
• Shirley, a California station on the Atchison, Topeka and Santa Fe Railway Valley Division, US

• Shirley (horse), an American Thoroughbred racehorse
• Shirley Institute, a cotton and textile research centre in Manchester
• Shirley Wind, a wind farm in Wisconsin, United States

• Shirley & Company, a 1970s disco group
• Shirley's World, a 1971 sitcom
• Skirlaugh, East Riding of Yorkshire, which has the same meaning as Shirley
• Upper Shirley (disambiguation)
• All pages with titles containing Shirley