Shenzhou or Shen Prefecture (Chinese: 深州) was a zhou (prefecture) in imperial China centering in modern Shenzhou, Hebei, China. It existed (intermittently) from 596 to 1913.

The modern city Shenzhou, established in 1994, retains its name.

• Shi Weile, ed. (2005). Zhongguo Lishi Diming Da Cidian (中国历史地名大词典) [Large Dictionary of Chinese Historical Place Names] (in Chinese). China Social Sciences Press. p. 2451. ISBN 7-5004-4929-1.