Shabu or syabu may refer to:

• Shabu, a slang term for the drug methamphetamine, used in Japan, Hong Kong, Philippines, Malaysia, Indonesia, and Saudi Arabia.
• Ya ba, also called shabú (Philippines), pills with a mixture of methamphetamine and caffeine prevalent throughout Asia.
• Shabu, a fictional genie from the sitcom Just Our Luck
• Shabu, one of the traditional dances of Himachal Pradesh
• Shabu, a name for tapioca in Bengali cuisine
• Shabu, Iran, (شبو), a village in South Khorasan Province, Iran
• Shabu, Qinzhou (沙埠镇), town in Qinnan District, Qinzhou, Guangxi, China
• Shabu, Taizhou, Zhejiang (沙埠镇), town in Huangyan District, Taizhou, Zhejiang, China

• Shabu-shabu, a Japanese variant of hot pot