Seeley is a variation of the Anglo-Norman Sealy surname. Notable people with the surname include:

• Alastair Seeley (born 1979), motorcycle racer, currently competing in the British Superbike Championship
• Blossom Seeley (1891–1974), American Vaudeville performer, teamed with Benny Fields
• Bob Seeley (born 1928), American boogie woogie pianist
• Colin Seeley (1936–2020), former motorcycle sidecar racer and motorcycle manufacturer
• Daniel Seeley (born 1984) English Footballer Ipswich Town fc and Cambridge United
• D. J. Seeley (born 1989), basketball player for Bayern Munich
• Drew Seeley (born 1982), a Canadian actor
• Elias P. Seeley (1791–1846), American Whig politician, 11th governor of New Jersey
• George Seeley (footballer) (1877–1921), English footballer with Southampton and Queens Park Rangers
• Gerald Seeley (1903–1941), English cricketer
• Harry Seeley (1839–1909), British paleontologist
• Ken Seeley (born 1962), American television personality
• Janet Seeley (1905–1987), American physical educator
• John Seeley (disambiguation), multiple people
• Mabel Seeley (1903–1991), American mystery book author
• Merritt W. Seely (often spelled "Seeley") (1813–1889), Wisconsin state senator
• Mildred Seeley (1918–2001), doll collector, doll-related entrepreneur and prolific author on the subjects of doll
• Richard Seeley (born 1979), Canadian ice hockey defenceman
• Robert Seeley (1602–1668), Puritan settler in Massachusetts Bay Colony
• Robert Thomas Seeley (1932–2016), American mathematician
• Stuart William Seeley (1901–1978), American electrical engineer
• Tim Seeley (fl. 2000s), American comic book artist
• Trish Seeley (born 1979), Funsized model
• Walter Seeley (1941–2019), American boxer
• William Henry Harrison Seeley (1840–1914), the first American citizen to be awarded the Victoria Cross