The Saturn Award for Best Network Television Series was presented annually by the Academy of Science Fiction, Fantasy and Horror Films, honoring the best network television series. It was introduced in 1988 and discontinued in 2015 when the Saturn Award went through major changes in their television categories.

Lost holds the record of the most wins in this category with five; additionally, Buffy the Vampire Slayer and The X-Files both won the award three times. The X-Files is also the most nominated series in the category, with eight nominations.

(NOTE: Year refers to year of eligibility, the actual ceremonies are held the following year)

The winners are listed in bold.

• 8 nominations - The X-Files (2 consecutive; 6 consecutive)
• 7 nominations:
  • Buffy the Vampire Slayer (consecutive)
  • Lost (consecutive)
  • The Simpsons (consecutive)
  • Smallville (6 consecutive)
• 6 nominations:
  • Angel (consecutive)
  • Star Trek: The Next Generation (consecutive)
  • Supernatural (2 consecutive; 3 consecutive)
• Fringe (consecutive)
• 4 nominations:
  • Heroes (consecutive)
  • Star Trek: Enterprise (consecutive)
• 3 nominations:
  • Alias (consecutive)
  • The Following (consecutive)
  • Star Trek: Voyager (2 consecutive)
  • Tales from the Crypt (2 consecutive)
• 2 nominations:
  • The Blacklist (consecutive)
  • CSI: Crime Scene Investigation (consecutive)
  • Dark Angel (consecutive)
  • Grimm
  • Hannibal (consecutive)
  • Once Upon a Time (consecutive)
  • Quantum Leap (consecutive)
  • Revolution (consecutive)
  • Roswell (consecutive)
  • Seven Days (consecutive)
  • Sleepy Hollow (consecutive)
  • Sliders (consecutive)
  • Star Trek: Deep Space Nine
  • Terminator: The Sarah Connor Chronicles (consecutive)
  • The Vampire Diaries (consecutive)
  • Veronica Mars (consecutive)

• 5 wins - Lost (2 consecutive; 3 consecutive)
• 3 wins:
  • Buffy the Vampire Slayer (2 consecutive)
  • The X-Files
• 2 wins:
  • Fringe (consecutive)
  • Hannibal (consecutive)
  • Revolution (consecutive)
  • Star Trek: The Next Generation (consecutive)

• Saturn Award for Best Action-Thriller Television Series
• Saturn Award for Best Animated Series or Film on Television
• Saturn Award for Best Fantasy Television Series
• Saturn Award for Best Horror Television Series
• Saturn Award for Best Science Fiction Television Series
• Saturn Award for Best Syndicated/Cable Television Series
• Saturn Award for Best Youth-Oriented Television Series

• Official Site
• Internet Movie Database: 16th, 17th, 18th, 19th, 20th, 21st, 22nd, 23rd, 24th, 25th, 26th, 27th, 28th, 29th, 30th, 31st, 32nd, 33rd, 34th, 35th, 36th, 37th, 38th, 39th, 40th, 41st