SHC2

SHC2
Identifiers
Aliases	SHC2, SCK, SHCB, SLI, SHC adaptor protein 2
External IDs	OMIM: 605217; MGI: 106180; HomoloGene: 19127; GeneCards: SHC2; OMA:SHC2 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	461,033 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	79,473,752 bp
RNA expression pattern
	Top expressed in
	Top expressed in
	More reference expression data
	More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
	Sources:Amigo / QuickGO
Orthologs
	25759
	216148
	ENSG00000129946
	ENSMUSG00000020312
	P98077
	Q8BMC3
	NM_012435; NM_001387056
	NM_001024539
	NP_036567
	NP_001019710
	Wikidata
View/Edit Human	View/Edit Mouse

SHC-transforming protein 2 is a protein that in humans is encoded by the SHC2 gene.^[5]^[6]^[7]

Interactions

Choy KW, Wang CC, Ogura A, et al. (2007). "Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes". Physiol. Genomics. 25 (1): 9–15. doi:10.1152/physiolgenomics.00121.2005. PMID 16368877.
Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. Bibcode:2004Natur.428..529G. doi:10.1038/nature02399. PMID 15057824.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Liu HY; Meakin SO (2002). "ShcB and ShcC activation by the Trk family of receptor tyrosine kinases". J. Biol. Chem. 277 (29): 26046–56. doi:10.1074/jbc.M111659200. PMID 12006576.
Warner AJ, Lopez-Dee J, Knight EL, et al. (2001). "The Shc-related adaptor protein, Sck, forms a complex with the vascular-endothelial-growth-factor receptor KDR in transfected cells". Biochem. J. 347 (Pt 2): 501–9. doi:10.1042/0264-6021:3470501. PMC 1220983. PMID 10749680.
Pelicci G, Dente L, De Giuseppe A, et al. (1996). "A family of Shc related proteins with conserved PTB, CH1 and SH2 regions". Oncogene. 13 (3): 633–41. PMID 8760305.