Royal Exchange may refer to:

• North East Quarter, Belfast, a planned city centre development formerly known as Royal Exchange.
• Royal Exchange, Dublin, now City Hall, Dublin
• Royal Exchange, Edinburgh, now the Edinburgh City Chambers
• Royal Exchange, London, a centre of commerce in the City of London
• Royal Exchange, Manchester, a 19th-century classical building, home of the Royal Exchange Theatre
• Royal Exchange (New York), former market and meeting hall
• The Royal Exchange (film), 2017 Belgian-French film

• Royal Exchange Assurance Corporation, a London insurance company
• Royal Exchange Hotel, Brisbane, a popular pub
• Royal Exchange Square