Protein-coding gene in the species Homo sapiens
RPS28 Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0 , 4V6X , 5A2Q , 5AJ0 , 3J7P , 4KZX , 4UJE , 4KZY , 4D5L , 4KZZ , 3J7R , 4UJD , 5FLX , 4D61 , 4UJC
Identifiers Aliases RPS28 External IDs OMIM : 603685 ; MGI : 1859516 ; HomoloGene : 68150 ; GeneCards : RPS28 ; OMA :RPS28 - orthologs Wikidata
40S ribosomal protein S28 is a protein that in humans is encoded by the RPS28 gene .[ 5] [ 6] [ 7]
Ribosomes , the organelles that catalyze protein synthesis , consist of a small 40S subunit and a large 60S subunit . Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S28E family of ribosomal proteins. It is located in the cytoplasm . As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[ 7]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000233927 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000067288 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Hori N, Murakawa K, Matoba R, Fukushima A, Okubo K, Matsubara K (Nov 1993). "A cDNA sequence of human ribosomal protein, homologue of yeast S28" . Nucleic Acids Res . 21 (18): 4394. doi :10.1093/nar/21.18.4394 . PMC 310080 PMID 8415000 . ^ Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes" . Genome Res . 8 (5): 509– 23. doi :10.1101/gr.8.5.509 PMID 9582194 . ^ a b "Entrez Gene: RPS28 ribosomal protein S28" .
Further reading
Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins". Biochem. Cell Biol . 73 (11– 12): 933– 47. doi :10.1139/o95-101 . PMID 8722009 . Vladimirov SN, Ivanov AV, Karpova GG, et al. (1996). "Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry" . Eur. J. Biochem . 239 (1): 144– 9. doi :10.1111/j.1432-1033.1996.0144u.x PMID 8706699 . Yoshihama M, Uechi T, Asakawa S, et al. (2002). "The human ribosomal protein genes: sequencing and comparative analysis of 73 genes" . Genome Res . 12 (3): 379– 90. doi :10.1101/gr.214202 . PMC 155282 PMID 11875025 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899– 903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121– 7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Yu Y, Ji H, Doudna JA, Leary JA (2005). "Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes" . Protein Sci . 14 (6): 1438– 46. doi :10.1110/ps.041293005 . PMC 2253395 PMID 15883184 . Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein–protein interaction network: a resource for annotating the proteome" . Cell . 122 (6): 957– 68. doi :10.1016/j.cell.2005.08.029 . hdl :11858/00-001M-0000-0010-8592-0 PMID 16169070 . S2CID 8235923 . Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein–protein interaction network". Nature . 437 (7062): 1173– 8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 . Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes" . Genome Res . 16 (1): 55– 65. doi :10.1101/gr.4039406 . PMC 1356129 PMID 16344560 . Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89. doi :10.1038/msb4100134 . PMC 1847948 PMID 17353931 .
