Q101 may refer to:

• Archive Series No. 2: Live in Chicago Q101, a live broadcast 'studio' album released by Violent Femmes in 2006
• CKMQ-FM, Merritt, British Columbia, Canada
• KQDJ-FM, Valley City, North Dakota
• WKQX (FM), an alternative rock station in Chicago, Illinois
• WICO-FM, Snow Hill, Maryland (former incarnation)
• WJAQ, Marianna, Florida (former incarnation)
• WJDQ, Meridian, Mississippi
• WQPO, Harrisonburg, Virginia
• Q101 Chicago
• Q101 (New York City bus)
• Q100 (New York City bus) (formerly the Q101R)
• Quran 101, the 101st chapter of the Islamic Holy book