Pierotti is an Italian surname. Notable people with the surname include:

• Al Pierotti (1895–1964), American football and baseball player
• Ermete Pierotti (1820–c.1880), Italian architect and engineer
• Giuseppe Pierotti (1826–1884), Italian sculptor and painter
• John Pierotti (1911–1987), American editorial cartoonist
• Juan Mencarini Pierotti (1860–1939), Spanish mid-rank employee of the Chinese Maritime Customs Service
• Mario Rubén González Pierotti (born 1949), Argentine singer-songwriter, artistically known as Jairo
• Muriel Pierotti (1897–1982), English feminist and trade unionist
• Piero Pierotti (1912–1970), Italian director, screenwriter and journalist
• Raffaele Pierotti (1836–1905), Italian cardinal and theologian
• Raquel Pierotti (born 1952), Uruguayan mezzo-soprano opera singer
• Santiago Pierotti (born 2001), Argentine professional footballer

• All pages with titles containing Pierotti
• Pieretti (disambiguation)