Petrelli is an Italian surname. Notable people with the surname include:

• Elia Petrelli (born 2001), Italian football player
• Italo Petrelli, Italian bobsledder
• Sergio Petrelli (born 1944), Italian football player
• Valentino Petrelli (1922–2001), Italian photographer

• Several characters of the Heroes
  • Peter Petrelli, portrayed by Milo Ventimiglia
  • Nathan Petrelli, portrayed by Adrian Pasdar
  • Angela Petrelli, portrayed by Cristine Rose
  • Arthur Petrelli
  • Heidi Petrelli
  • Simon & Monty Petrelli