Paul Lewis may refer to:

• Paul Lewis (field hockey) (born 1966), Australian field hockey player
• Paul Lewis (footballer) (born 1994), British association footballer
• Paul Lewis (racing driver) (born 1932), American NASCAR driver
• Paul Lewis (soccer) (born 1999), American association footballer (soccer player)

• Paul Lewis (architect), American architect and professor at the Princeton University School of Architecture
• Paul Lewis (broadcaster) (born 1948), British radio broadcaster and financial journalist
• Paul Lewis (journalist) (born 1981), British newspaper journalist
• Paul Lewis (professor), American professor of literature
• Paul Lewis (pianist) (born 1972), English classical pianist
• Paul Lewis (politician), Montserratian politician
• Paul A. Lewis (1879–1929), American pathologist at the University of Pennsylvania and the Rockefeller Institute
• Paul H. Lewis, professor of political science at Tulane University
• Paul M. Lewis (car builder) (died 1990), American entrepreneur and car builder
• Paul M. Lewis (diplomat), appointed to help shut down the Guantanamo prison