Papareschi is an Italian surname, and may refer to:

• House of Papareschi (also De Papa or Paparoni) a noble family of medieval Rome. To it belong:
  • Gregorio Papareschi (cardinal) (12th century), cardinal-nephew of Pope Innocent II
  • Gregorio Papareschi (died 1143), Italian pope (Innocent II)
  • Pietro Papareschi (12th century), cardinal-nephew of Pope Innocent II
  • Romano Bonaventura (died 1243), also listed as Romano Papareschi