An orphan is one who has lost both parents.

Orphan(s) or The Orphan(s) may also refer to:

• The Orphan (1960 film), a Hong Kong film starring Bruce Lee
• The Orphan, a 1979 horror film starring Peggy Feury and Joanna Miles
• The Orphan (2018 film), a Brazilian short drama film
• Orphan (2009 film), a psychological thriller film directed by Jaume Collet-Serra
• Orphan (2016 film), a French film
• The Orphan (2018 film), a Brazilian film directed by Carolina Markowicz
• Orphans (1987 film), an American film by Alan J. Pakula, based on the play by Lyle Kessler (see below)
• Orphan: First Kill, a 2022 American psychological horror film, prequel to the 2009 film
• Orphans (1998 film), a Scottish film by Peter Mullan
• "The Orphan" (Alias), a television episode
• Orphan film, a film abandoned by its owner or copyright holder, or any film that has suffered neglect

• The Orphans series, a 1998 novel series attributed to V. C. Andrews, by Andrew Neiderman
• Orphan (DC Comics), a superheroine associated with Batman
• Orphan (Marvel Comics), a character in the X-Statix series
• The Orphan, a 1980 novel by Robert Lester Stallman

• Orphan (Darwin's Waiting Room album), 2001
• Orphan (Empires album) or the title song, 2014
• Orphans: Brawlers, Bawlers & Bastards, by Tom Waits, 2006
• The Orphans, by Kristeen Young, 2006
• Orphans (EP), by Charlotte Martin, 2008

• "Orphans" (Beck song), 2008
• "Orphans" (Coldplay song), 2019
• "Orphans", by Impending Doom from There Will Be Violence, 2010
• "Orphan", by In Hearts Wake from Incarnation, 2024
• "Orphan", by Silent Planet from Everything Was Sound, 2016
• "Orphan", by Slipknot from We Are Not Your Kind, 2019
• "Orphan", by Toto from Toto XIV, 2015
• "Orphan", by Whitechapel from Kin, 2021
• "The Orphan", by Amorphis from Elegy, 1996
• "The Orphan", a composition by Modest Mussorgsky, 1871
• "Orphaned", a 2006 song from No Heroes by Converge

• The Orphan (play), a 1680 play by Thomas Otway
• Orphans (Lyle Kessler play), a 1983 play by Lyle Kessler
• Orphans (Dennis Kelly play), a 2009 play by Dennis Kelly

• Les Orphan (1923–1995), Welsh footballer
• Victoria Orphan, American geobiologist
• Mikołaj Krzysztof "the Orphan" Radziwiłł (1549–1616), Polish-Lithuanian nobleman, Grand Marshal of Lithuania, voivode and Imperial Prince of the Holy Roman Empire

• Orphan (car), any marque of motor vehicle built by a manufacturer that has discontinued business entirely
• Orphan Basin, an Atlantic Ocean area off Newfoundland and Labrador, Canada
• Orphan Knoll, an undersea peak, horst and continental fragment in the Atlantic Ocean off Newfoundland
• Orphan (typesetting), the first line of a paragraph appearing at the bottom of a page
• Cambridge Orphans, a minor league baseball team based in Cambridge, Massachusetts, in 1899
• Sirotci or Orphans, a regional faction of Hussites
• The Orphan (painting), an 1834 painting by William Allan

• Orphan disease, a rare disease
• Orphan drug, one developed under the 1983 U.S. Orphan Drug Act for orphan diseases
• Orphan process, a computer process whose parent process has finished
• Orphan receptor, apparent receptor that has a similar structure to other identified receptors but whose endogenous ligand has not yet been identified
• Orphan source, a self-contained radioactive source that is no longer under proper regulatory control
• Orphaned technology, technology that has been abandoned by its original developers
• Orphan works, copyrighted works whose holder is hard to find