Orestrate
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| Other names | Estradiol 3-propionate 17β-(1-cyclohexenyl) ether; 17β-(Cyclohexen-1-yloxy)-estra-1,3,5(10)-trien-3-ol propionate |
| Drug class | Estrogen; Estrogen ester |
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| Chemical and physical data | |
| Formula | C27H36O3 |
| Molar mass | 408.582 g·mol−1 |
| 3D model (JSmol) | |
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Orestrate (INN), also known as estradiol 3-propionate 17β-(1-cyclohexenyl) ether, is an estrogen medication and estrogen ester which was never marketed.[1][2][3][4][5] It is the C3 propionate ester and C17β-(1-cyclohexenyl) ether of estradiol.[1][5]
See also
References
- ^ a b Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 898, 905. ISBN 978-1-4757-2085-3.
- ^ Gardi R, Vitali R, Falconi G, Ercoli A (February 1973). "1,3,5(10)-Estratrien-17 -yl enol ethers and acetals. New classes of orally and parenterally active estrogenic derivatives". Journal of Medicinal Chemistry. 16 (2): 123–127. doi:10.1021/jm00260a009. PMID 4683106.
- ^ Galletti F, Gardi R (April 1974). "Effect of two orally active estradiol derivatives on sulfobromphthalein retention in rats". Pharmacological Research Communications. 6 (2): 135–145. doi:10.1016/s0031-6989(74)80021-4. PMID 4438394.
- ^ List PH, Hörhammer L (12 March 2013). "Orestratum". Chemikalien und Drogen Teil A: N-Q. Springer-Verlag. pp. 331–. ISBN 978-3-642-65035-2.
- ^ a b Roche EB, Academy of Pharmaceutical Sciences, ((Medicinal Chemistry Section (1977). Design of biopharmaceutical properties through prodrugs and analogs: a symposium. The Academy. p. 7. ISBN 978-0-917330-16-2.