Nicolae Crețulescu (Nicolae Kretzulescu)
2nd Prime Minister of Romania
In office 24 June 1862 – 11 October 1863 14 June 1865 – 11 February 1866
Monarch	Alexandru Ioan Cuza
Preceded by	Barbu Catargiu Mihail Kogălniceanu
Succeeded by	Mihail Kogălniceanu Lascăr Catargiu
Minister of Internal Affairs
In office 24 June 1862 – 11 October 1863 30 January 1866 – 11 February 1866
Prime Minister	himself
Preceded by	Apostol Arsache Ion Emanuel Florescu
Succeeded by	Mihail Kogălniceanu] Dimitrie Ghica
President of the Senate of Romania
In office 13 December 1889 – 9 June 1890
Monarch	Carol I
Preceded by	Ion Emanuel Florescu
Succeeded by	Ion Emanuel Florescu
Personal details
Born	(1812-03-01)March 1, 1812 Bucharest, Wallachia
Died	26 June 1900(1900-06-26) (aged 88)[1] Leordeni, Argeș County, Kingdom of Romania
Resting place	Bellu Cemetery, Bucharest
Political party	National Liberal Party
Children	Ana Crețulescu-Lahovary
Parents	Alexandru Crețulescu (father) Ana Anica Câmpineanu de Cantimir (mother)
Relatives	Constantin A. Crețulescu, Scarlat Kretzulescu [ro] (brothers)
Occupation	Physician, politician

Prince Nicolae Crețulescu (Romanian pronunciation: [nikoˈla.e kret͡suˈlesku], surname also spelled Kretzulescu; 1 March 1812 – 26 June 1900) was a Prince Wallachian, later Romanian politician and physician. He is an aristocrat and member of the Kretzulescu family. He served two terms as Prime Minister of Romania: from 1862 to 1863, and from 1865 to 1866. He was elected to the Romanian Academy. He was the 3rd president of the Romanian Academy from 1872 to 1873.

Born in Bucharest, he studied medicine in Paris, having Gustave Flaubert as a colleague. As a physician, his notable work was the translation of Jean Cruveilhier's manual of anatomy.

A member of the Liberal faction, Crețulescu first became prime minister after the assassination of Barbu Catargiu, under ruler Alexandru Ioan Cuza. He avoided debating the issue of land reform, at that time the most contentious subject in Romanian politics; instead, Crețulescu focused on unifying the public health system, creating the Directorate General of the Public Archive, and establishing a Council for Public Instruction. Additionally, he laid the groundwork for further laws secularizing the property of monasteries.