Natalie may refer to:

• Natalie, Michigan, an unincorporated community

• Natalie (given name)
• Natalie (singer) (born 1979), Mexican-American R&B singer/songwriter
• Beby Natalie [id] (born 1999), better known as Natalie Zenn, Indonesian actress and singer
• Shahan Natalie (1884–1983), Armenian writer and principal organizer of Operation Nemesis
• Natalie Sarah [id] (born 1983), Indonesian actress

• Natalie (Natalie album), by Natalie Alvarado, 2005
• Natalie (Natalie Cole album), 1976

• "Natalie" (Ola song), 2006
• "Natalie", by Ada LeAnn, representing Michigan in the American Song Contest, 2022
• "Natalie", by Bruno Mars from Unorthodox Jukebox, 2012
• "Natalie", by Dave Rowland, 1982
• "Natalie", by Freddy Cannon, 1966
• "Natalie", by Rich Dodson, 1980
• "Natalie", by Shirley Bassey from I Am What I Am, 1984
• "Natalie", by Stephen Duffy, 1993

• Natalie (film), a 2010 South Korean film
• Natalie (website), a Japanese entertainment news website

• Natalee, a given name
• Natali (disambiguation)
• Nathalie (disambiguation)