NRS may refer to:

• Name Registration Scheme, naming scheme by JANET used on British academic and research networks in the 1980
• National Readership Survey, a joint venture company in the UK providing audience research for print advertising
  • NRS social grade, a system of demographic classification and a standard for market research
• National Records of Scotland, the Scottish government department responsible for civil registration, the census in Scotland, demography and statistics, family history and the national archives and historical records.
• National Relay Service, an Australian government initiative for people who are deaf or have a hearing or speech impairment
• National Reporter System, a set of case law reporters in the United States
• National Retail Systems Inc., a global logistics and trucking company
• National Runaway Switchboard, a national US hotline for youth in crisis
• Nederlandsche Rhijnspoorweg-Maatschappij, a former Dutch railway company (1845-1890)
• NetherRealm Studios, an American video game developer known for the Mortal Kombat series
• Nevada Revised Statutes, Nevada laws
• New Regeneration System, a process used for sugar thin-juice decalcification in beet sugar factories
• Nil Ratan Sircar Medical College and Hospital, a renowned public medical school and hospital in Kolkata, India
• Non-rocket spacelaunch, concepts for spacelaunch speed and altitude are provided by something other than rockets
• Norman-Roberts syndrome, a brain disorder
• Norwegian Air UK, airline with ICAO designator NRS
• Nuclear Restoration Services, a trading name of Magnox Ltd
• Numerical Rating Scale, a scale for pain