N12 may refer to:

• N12 (South Africa)
• N12 road (Ghana)
• N12 road (Ireland)
• Nebraska Highway 12, United States
• Route nationale 12, France

• N12 (Art Group), China
• HMS Clyde (N12), a submarine of the Royal Navy
• N12, the website for Hevrat HaHadashot (the News division for the Israeli Channel 12)
• Interstitial nephritis
• Lakewood Airport, New Jersey, United States
• LNER Class N12, a class of British steam locomotives
• Nissan Pulsar (N12), a Japanese car
• Nitrogen-12, an isotope of nitrogen
• Nylon 12, a polymer
• N12, a postcode district in the N postcode area, North London, England

• 12N (disambiguation)