Monkey Business may refer to:

• Monkey Business (1925 film), a Krazy Kat cartoon
• Monkey Business (1926 film), an Our Gang comedy
• Monkey Business (1931 film), a Marx Brothers comedy
• Monkey Business (1952 film), directed by Howard Hawks with Cary Grant
• Monkey Business (2022 film), directed by Daniel Guzmán
• Monkey Business (TV series), a British documentary series
• Hera Pheri (2000 film) or Monkey Business, a 2000 Indian comedy film by Priyadarshan
• "Monkey Business", an episode of Californication

• Monkey Business (band), a Czech funk band
• Monkey Business (Black Eyed Peas album), 2005
• Monkey Business (Margaret album), 2017
• "Monkey Business" (Skid Row song), 1991
• "Monkey Business" (Michael Jackson song), released 2004
• "Monkey Business", a song by Nik Kershaw on the album Human Racing
• "Monkey Business", a song by Pain on the album Cynic Paradise
• "Monkey Business", a song by Danger Danger on the album Screw It!
• "Monkey Business", a song by Pet Shop Boys on the album Hotspot

• Monkey Business (yacht), gained noteriety during the 1987 political scandal involving presidential candidate Gary Hart
• "Monkey Business" (short story), by P. G. Wodehouse
• Monkey Business, a 1987 children's book by Mark Burgess
• (monkey) Business, an early name for the DotA 2 eSports team OG

• "Monkey Bizness", a recurring comic strip in The Dandy magazine
• "Too Much Monkey Business", a 1956 song by Chuck Berry, covered by several artists
• Hera Pheri (disambiguation), title of various Indian films (lit. 'Monkey Business')