Mollison is a surname. Notable people with the surname include:

• Bill Mollison (1928–2016), researcher, author, scientist, teacher and naturalist
• Clifford Mollison (1897–1986), British film and television actor
• Deborah Mollison (born 1958), British composer and songwriter
• Derek Mollison (1901–1943), Australian footballer and businessman
• Fiona Mollison (born 1954), British television and theatre actress
• Henry Mollison (1905–1985), British film actor
• Irvin C. Mollison (1898–1962), American judge
• James Mollison, AO, (1931–2020), director of the National Gallery of Australia
• James William Mollison (1858–1927), British agriculture specialist in India
• Jim Mollison (1905–1959), Scottish pioneer aviator who set many records
• Sam Mollison, electronic music producer and vocalist
• William Loudon Mollison (1851–1929), Scottish mathematician and academic
• Willis Elbert Mollison (1859–1924), American teacher, newspaper editor, politician, banker, businessman, lawyer, public official, and civil rights advocate
• Lindsay Mollison Australian physician and environmentalist