The 16th congressional district of Missouri was a congressional district for the United States House of Representatives in Missouri from 1903 to 1933.

Member	Party	Years	Cong ress	Electoral history
District created March 4, 1903
J. Robert Lamar (Houston)	Democratic	March 4, 1903 – March 3, 1905	58th	Elected in 1902. Lost re-election.
Arthur P. Murphy (Rolla)	Republican	March 4, 1905 – March 3, 1907	59th	Elected in 1904. Lost re-election.
J. Robert Lamar (Houston)	Democratic	March 4, 1907 – March 3, 1909	60th	Elected in 1906. Lost re-election.
Arthur P. Murphy (Rolla)	Republican	March 4, 1909 – March 3, 1911	61st	Elected in 1908. Lost re-election.
Thomas L. Rubey (Lebanon)	Democratic	March 4, 1911 – March 3, 1921	62nd 63rd 64th 65th 66th	Elected in 1910. Re-elected in 1912. Re-elected in 1914. Re-elected in 1916. Re-elected in 1918. Lost re-election.
Samuel A. Shelton (Marshfield)	Republican	March 4, 1921 – March 3, 1923	67th	Elected in 1920. Retired.
Thomas L. Rubey (Lebanon)	Democratic	March 4, 1923 – November 2, 1928	68th 69th 70th	Elected in 1922. Re-elected in 1924. Re-elected in 1926. Died.
Vacant		November 2, 1928 – March 3, 1929	70th
Rowland L. Johnston (Rolla)	Republican	March 4, 1929 – March 3, 1931	71st	Elected in 1928 Lost re-election.
William E. Barton (Houston)	Democratic	March 4, 1931 – March 3, 1933	72nd	Elected in 1930 Redistricted to at-large district and lost renomination.
District eliminated March 4, 1933

• Election Statistics 1920-present Clerk of the House of Representatives
• Martis, Kenneth C. (1989). The Historical Atlas of Political Parties in the United States Congress. New York: Macmillan Publishing Company.
• Martis, Kenneth C. (1982). The Historical Atlas of United States Congressional Districts. New York: Macmillan Publishing Company.
• Congressional Biographical Directory of the United States 1774–present