Michael or Mike Barber may refer to:

• Sir Michael Barber (educationist) (born 1955), British educationist
• Michael C. Barber (born 1954), Roman Catholic bishop of Oakland
• Michael Barber (chemist) (1934–1991), developer of fast atom bombardment
• Michael Barber (academic) (born 1947), Australian mathematician, physicist and academic
• Michael J. Barber (born 1960), American engineer

• Mike Barber (tight end) (born 1953), American football tight end and minister
• Mike Barber (linebacker) (born 1971), American football linebacker
• Michael Barber (wide receiver) (born 1967), American football wide receiver
• Michael Barber (athlete) (born 2000), Canadian Paralympic runner

• Ray Barber (Michael Joseph Barbetta, 1923–2009), American singer
• Mikele Barber (born 1980), American track and field sprint athlete