Mel Brown may refer to:

• Mel Brown (basketball) (1935–2019), Canadian basketball player
• Mel Brown (drummer) (born 1944), American jazz musician
• Mel Brown (guitarist) (1939–2009), blues guitarist
• Mel Brown (footballer) (1911–1995), Australian rules footballer
• Melanie Brown (born 1975), English singer, formerly of the Spice Girls

• Melvin Brown (disambiguation)
• Melissa Brown (disambiguation)
• Melville Brown (disambiguation)