María Pérez may refer to:

• María Pérez Balteira (fl. 13th-century), Galician composer and singer
• María Angélica Pérez (1897–1932), Argentine Roman Catholic nun
• María del Pilar Pérez (born 1951), Chilean architect convicted of murder
• María Irigoyen Pérez (born 1952), Spanish member of the European Parliament
• María Pérez (swimmer) (born 1962), Venezuelan Olympic swimmer
• María José Pérez (footballer) (born 1984), Spanish footballer
• María Belén Pérez Maurice (born 1985), Argentine fencer
• María Luisa Pérez-Soba (1930–2021) first woman agricultural engineer in Galicia
• María Isa Pérez-Vega, American politician and musician
• María Pérez Fernández (born 1987), Spanish footballer
• María José Pérez (footballer) (born 1984), Spanish association football player
• María José Pérez (volleyball) (born 1988), Venezuelan volleyball player
• María Pérez (judoka) (born 1989), Puerto Rican judoka
• María Isabel Pérez (footballer) (born 1992), Cuban footballer
• María José Pérez (runner) (born 1992), Spanish runner
• María Isabel Pérez (born 1993), Spanish sprinter
• María Jimena Pérez (born 1984), Argentine volleyball player
• María Pérez (racewalker) (born 1996), Spanish racewalker
• María Paulina Pérez (born 1996), Colombian tennis player
• Maria Vergés Pérez, Spanish politician and musician
• María Fernanda Pérez (born 1995), Mexican footballer
• María Pérez (Spanish footballer) (born 2001), Spanish footballer
• Maria Perez (journalist), American journalist for the Naples Daily News; see List of George Polk Award winners
• Maria Perez (New Hampshire politician)