List of reference ranges for cerebrospinal fluid
| Reference ranges |
|---|
|
In: |
Following is a list of reference ranges for cerebrospinal fluid:
Ions and metals
| Substance | Lower limit | Upper limit | Unit | Corresponds to % of that in plasma[clarification needed] |
|---|---|---|---|---|
| Osmolality | 280[1] | 300[1] | mmol/L | |
| Sodium | 135[1] | 150[1] | mmol/L | |
| Potassium | 2.6[1] | 3.0[1] | mmol/L | |
| Chloride | 115[1] | 130[1] | mmol/L | >100%[1] |
| Calcium | 1.00[1] | 1.40[1] | mmol/L | ~50%[1] |
| Magnesium | 1.2[1] | 1.5[1] | mmol/L | >100%[1] |
| Iron | 0.2[1] | 0.4[1] | μmol/L |
Other molecules
| Substance | Lower limit | Upper limit | Unit | Corresponds to % of that in plasma |
|---|---|---|---|---|
| Glucose | 50[2] | 80[2] | mg/dL | ~60%[1] |
| 2.2,[3] 2.8[1] | 3.9,[3] 4.4[1] | mmol/L | ||
| Protein | 15[1][2] | 40,[4] 45[1][2] | mg/dL | ~1%[1] |
| Albumin | 7.8[5] | 40[5] | mg/dL | 0[6] - 0.7%[6] - corresponding to an albumin (CSF/serum) quotient of 0 to 7x10−3 |
| Lactate | 1.1[1] | 2.4[1] | mmol/L | |
| Creatinine | 50[1] | 110[1] | μmol/L | |
| Phosphorus | 0.4[1] | 0.6[1] | μmol/L | |
| Urea | 3.0[1] | 6.5[1] | mmol/L | |
| Carbon dioxide | 20[1] | 25[1] | mmol/L |
Other CSF constituents
| Substance | Lower limit | Upper limit | Unit | Corresponds to % of that in blood plasma |
|---|---|---|---|---|
| RBCs | n/a[2] | 0[2] / negative | cells/μL or cells/mm3 | |
| WBCs | 0[2] | 3[2] | cells/μL cells/mm3 | |
| pH | 7.28[1] | 7.32[1] | (-log M) | |
| PCO2 | 44[1] | 50[1] | mmHg | |
| 5.9[7] | 6.7[7] | kPa | ||
| PO2 | 40[1] | 44[1] | mmHg | |
| 5.3[7] | 5.9[7] | kPa |
References
- ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an PATHOLOGY 425 CEREBROSPINAL FLUID [CSF] Archived 2005-10-27 at the Wayback Machine at the Department of Pathology and Laboratory Medicine at the University of British Columbia. By Dr. G.P. Bondy. Retrieved November 2011 [dead link]
- ^ a b c d e f g h Normal Reference Range Table Archived 2011-12-25 at the Wayback Machine from The University of Texas Southwestern Medical Center at Dallas. Used in Interactive Case Study Companion to Pathologic basis of disease.
- ^ a b Department of Chemical Pathology at the Chinese University of Hong Kong Archived 2015-01-05 at the Wayback Machine, in turn citing: Roberts WL et al. Reference Information for the Clinical Laboratory. In Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 4th edn. Burtis CA, Ashwood ER and Bruns DE eds. Elsevier Saunders 2006; 2251 - 2318
- ^ Felgenhauer K (1974). "Protein size and CSF composition". Klin. Wochenschr. 52 (24): 1158–64. doi:10.1007/BF01466734. PMID 4456012. S2CID 19776406.
- ^ a b Lab Manual for SFGH > PROTEIN, CSF - IgG INDEX Archived 2015-01-05 at the Wayback Machine at The University of California, San Francisco. Last updated 10/4/2010.
- ^ a b Standardization of procedures and methods in neuroimmunology Archived 2013-10-21 at the Wayback Machine from the Italian Association of Neuroimmunology. Retrieved January, 2012
- ^ a b c d Derived from mmHg values using 0.133322 kPa/mmHg