Seychelles, officially the Republic of Seychelles, is a 115-island country spanning an archipelago in the Indian Ocean, some 1,500 kilometres (932 mi) east of mainland Southeast Africa, northeast of the island of Madagascar.

Since Seychelles' independence in 1976, per capita output in this Indian Ocean archipelago has expanded to roughly seven times the old near-subsistence level. Growth has been led by the tourist sector, which employs about 30% of the labor force and provides more than 70% of hard currency earnings, followed by tuna fishing. In recent years the government has encouraged foreign investment in order to upgrade hotels and other services. At the same time, the government has moved to reduce the dependence on tourism by promoting the development of farming, fishing, small-scale manufacturing and most recently the offshore sector. The vulnerability of the tourist sector was illustrated by the sharp drop in 1991-92 due largely to the Gulf War. Although the industry has rebounded, the government recognizes the continuing need for upgrading the sector in the face of stiff international competition.

This list includes notable companies with primary headquarters located in the country. The industry and sector follow the Industry Classification Benchmark taxonomy. Organizations which have ceased operations are included and noted as defunct.

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  An Air Seychelles Boeing 707-320C on short final to Paris Orly Airport in 1989.
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  A Lignes Aérienne Seychelles Boeing 707
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  A Seychelles International Airways Douglas DC-8 at Basle in 1985

• Economy of Seychelles
• List of airlines of Seychelles
• List of banks in Seychelles