Kathleen may refer to:

• Kathleen (given name)
• Kathleen (singer), Canadian pop singer

• Kathleen, Alberta, Canada
• Kathleen, Georgia, United States
• Kathleen, Florida, United States
• Kathleen High School (Lakeland, Florida), United States
• Kathleen, Western Australia, Western Australia
• Kathleen Island, Tasmania, Australia
• Kathleen Lumley College, South Australia
• Mary Kathleen, Queensland, former mining settlement in Australia

• Kathleen (film), a 1941 American film directed by Harold S. Bucquet
• The Countess Kathleen and Various Legends and Lyrics (1892), second poetry collection of William Butler Yeats
• Kathleen Ferrier Award, competition for opera singers
• Kathleen Mitchell Award, Australian literature prize for young authors
• Plan Kathleen, plan for a German invasion of Northern Ireland sanctioned by the IRA Chief of Staff in 1940
• Tropical Storm Kathleen (disambiguation)
• "Kathleen" (song), a song by Catfish and the Bottlemen
• "Kathleen", song by Wally Lewis
• Typhoon Kathleen, hit Japan in 1947