Kara-Murza (Russian: Кара́-Мурза́) is a surname of Tatar origin translated as "Black Prince" or "Dark Lord". Its Russified version is Karamzin (Russian: Карамзин). Kara Murza was a Tatar aristocrat who converted to Christianity after settling in Moscow in the 15th century. The following people share this last name:

• Kristapor Kara-Murza (1853–1902), Armenian composer
• Sergey Kara-Murza (born 1939), Soviet/Russian historian, chemist and philosopher
• Vladimir Alexeyevich Kara-Murza (1959–2019), Soviet/Russian TV anchor
• Vladimir Vladimirovich Kara-Murza (born 1981), Russian journalist and opposition politician