Kaffir or Kafir may refer to:

• Kafir, a term for a non-Muslim
• Kaffir (racial term), an ethnic slur used in South Africa
• The Nuristani people, an ethnic group of Pakistan and Afghanistan
• Sri Lanka Kaffir people, an ethnic group

• Fanagalo, a Zulu-based pidgin language once referred to as Kitchen Kaffir
• Sri Lanka Kaffir language, a creole spoken by that people
• Kafiiri or Kafiristani, terms for the Nuristani languages of the Hindu Kush

• Kaffraria or British Kaffraria, a former designation for King William's Town and East London, South Africa
• Kafir, Idlib, a village in Syria
• Kafiristan, the historic name for the Nuristan Province in Afghanistan
• Kaffrine, a city in Senegal

• Kaffir lime, a variety of lime fruit native to Indonesia also known as a makrut lime
• Kaffir lily (disambiguation), one of two flowers found in southern Africa:
  • Clivia miniata
  • Hesperantha coccinea
• Kafir, kaffir or kaffircorn, another name for the grain sorghum
• Kaffir boom (Erythrina lysistemon), a species of tree in the family Fabaceae

• Kaafir (Pakistani TV series), a 2011 television series
• Kaafir (Indian TV series), a 2019 Indian web television series
• Kafir harp
• Sunbeam Kaffir, an engine built by the Sunbeam car company
• African wildcat, formerly known as the Kaffir cat
• Kaffir-D Stone, the alpha form of gypsum (calcium sulphate hemihydrate; (CaSO4)2H2O) used in the manufacture of dentures.

• Kefir, fermented milk drink
• Cafres
• Tibicos, a fermented beverage known as water kefir
• Infidel